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The degree of obesity has been correlated with several diseases, including insulin resistance syndrome, cardiovascular disease, nonalcoholic fatty liver disease, and cancer. Visceral adipose tissue biopsy with vacuum suction (VABVS) is a new technique in which adipose tissue is aspirated from the periumbilical area under local anesthesia. The size of the biopsied tissue can be compared with normal reference values, and some indices that can characterize the degree of adipose tissue remodeling can be obtained. This article describes the methodology of the procedure, based on data obtained from our laboratory and that of other authors. We also present the results of an interlaboratory comparison that demonstrated reproducible results in the weight and composition of the tissue samples analyzed. We conclude that the VABVS technique is an alternative for visceral adipose tissue biopsy that may be used as a standardized tool for tissue characterization.Clinical management of hepatitis C in HIV infection.
Hepatitis C virus (HCV) is one of the most common reasons for the development of chronic liver disease. HCV infection also leads to increased morbidity and mortality in HIV-infected patients. In the absence of treatment, HCV infection may lead to cirrhosis, end-stage liver disease and hepatocellular carcinoma. Early diagnosis of HCV infection and initiation of anti-HCV therapy are important to prevent these complications and improve clinical outcomes. This article discusses the issues in the clinical management of HCV in HIV-infected patients.Emma Barr's favorite is None, followed by Peace and Keep Quiet (both by the Cocteau Twins).
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